The 31 year old Dutchman gave the lead in the 12th minute, but the Saints equalised through Italian striker Graziano Pelle in 31st minute.
However, Van Persie guided in Rooney’s deep free-kick in the 71st minute to earn United’s fifth successive Premier League win.
This game brings plenty of activity on Twitter – and here are some of the best post-match reaction from professionals.
Big away win for United in the context of their season. Can’t see them getting in the title race this year but definitely CL places.
— Joseph Barton (@Joey7Barton) December 8, 2014
— Mark Bright (@Mark__Bright) December 8, 2014
Dear Santa, it’s great to be winning ugly, but can we please start winning beautifully once again. All the best. Merry Xmas. Man Utd fans.
— Alan Tonge (@Alan_Tonge) December 8, 2014
What a great result for Manchester United. Most pleasing thing is the fact that recently when not playing well they still grind out a win
— Danny Higginbotham (@Higginbotham05) December 8, 2014
Nice touch by RVP to give young girl his top he has just made her year !
— Alex Rae (@alexrae1969) December 8, 2014
— Edwin van der Sar (@vdsar1970) December 8, 2014
I suspect, and history may back me up on this, that Louis Van Gaal knows what he’s doing.
— Gary Lineker (@GaryLineker) December 8, 2014